Mystery Diagnosis (2005)

Biography · Documentary · Mystery

Mystery Diagnosis is a television program that airs on the OWN: Oprah Winfrey Network. Each episode focuses on two or more individuals and their struggles to find out what ailments they suffer from. As the program's title suggests, doctors have a difficult time finding a diagnosis, often due to nonspecific symptoms, the rarity of the condition or disease, or the patient's case being an unusual manifestation of said condition or disease. The series debuted on Discovery Health Channel in 2005, and was continued when the Oprah Winfrey Network replaced Discovery Health on January 1, 2011; the current season premiered January 5, 2011.

IMDb rating: 8.2 (332 votes)
Seasons: 7
Language: EN
Type: TV series

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Ratings refreshed Aug 19, 2026 · 7 seasons indexed

Seasons

Season 3 (2005)

8.86 avg 7 episodes 8.0 → 9.0 43 min avg

Season 3 episodes - IMDb ratings
#	Title	Rating	Votes
1	Sleeping Beauty	8.0	7
3	Deadly Sore Throat	9.0	6
4	The 13 Year Stomach Ache	9.2	7
5	The Bearded Lady	8.8	6
6	The Boy Who Couldn't Breathe	9.0	6
8	The Baby Who Changed Colors	9.0	6
10	Not a Normal Newborn	9.0	6

Season 5 (2008)

9.10 avg 7 episodes 9.2 → 9.2 43 min avg

Season 5 episodes - IMDb ratings
#	Title	Rating	Votes
1	The Girl Who Couldn't Be Touched	9.2	6
2	The Girl Who Gagged	9.2	6
3	The Woman Who Kept Falling Down	9.3	7
5	The Girl Nobody Believed	8.8	6
6	The Headache That Wouldn't Go Away	8.7	7
9	The Woman Who Couldn't Cry	9.3	7
10	The Woman with a Knife in Her Head	9.2	7

Season 6 (2008)

8.27 avg 7 episodes 7.8 → 9.0 43 min avg

Slow burn

Season 6 episodes - IMDb ratings
#	Title	Rating	Votes
1	The Woman with the Giant Lump	7.8	7
2	The Woman Who Couldn't Stop Rocking	7.8	6
6	The Boy Who Kept Swelling	8.4	8
7	The Boy Who Stopped Walking	7.8	7
8	The Boy Who Bit Himself	7.9	7
10	The Black and Blue Baby	9.2	5
11	The Baby Who Couldn't Stop Eating	9.0	5

Season 7 (2009)

7.80 avg 3 episodes 7.7 → 7.9 43 min avg

Rising

Season 7 episodes - IMDb ratings
#	Title	Rating	Votes
3	The Girl with Holes in Her Jaw	7.7	7
5	The Woman Who Couldn't Stop Burping	7.8	6
7	The Girl with Half a Face	7.9	7

Season 8 (2009)

8.05 avg 6 episodes 8.3 → 8.4 43 min avg

Season 8 episodes - IMDb ratings
#	Title	Rating	Votes
1	The Woman Whose Legs Turned Black	8.3	7
2	The Man Who Tripled in Size	7.8	6
3	The Girl Who Stopped Growing	8.4	8
4	The Boy with the Strange Stare	7.5	6
6	The Baby Who Smelled Like Pancakes	7.9	7
8	The Girl Who Was Covered in Bumps	8.4	6

Season 9 (2010)

8.14 avg 9 episodes 8.0 → 7.9 42 min avg

Mid-peak

Season 9 episodes - IMDb ratings
#	Title	Rating	Votes
1	The Woman Whose Flesh Was Eaten Alive	8.0	6
2	The Boy Who Only Hopped	8.4	7
3	The Man with Hundreds of Lumps	7.8	6
4	The Baby Who Bruised Easily	7.5	7
5	The Girl with No Bowel	8.2	6
7	The Toddler That Went Through Puberty	8.8	8
8	The Toddler Who Stopped Walking	8.7	10
9	The Woman with Unusual DNA	8.0	8
10	The Boy with the 150 Pound Leg	7.9	7

Season 10 (2011)

8.46 avg 7 episodes 7.5 → 8.7

Season 10 episodes - IMDb ratings
#	Title	Rating	Votes
1	Fight to the Last Breath	7.5	6
2	Trapped Inside Their Bodies	8.6	5
3	Dangerous Growths	8.6	5
4	When the Body Shuts Down	8.5	6
5	A Family's Desperate Search	8.7	6
7	Too Young to be Sick	8.6	7
9	Stolen Senses	8.7	6